MCM6 Antikörper
Kurzübersicht für MCM6 Antikörper (ABIN6569004)
Target
Alle MCM6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Aufreinigung
- Affinity purification
-
Immunogen
- Recombinant fusion protein of human MCM6 (NP_005906.2).
-
Isotyp
- IgG
-
-
anti-Minichromosome Maintenance Complex Component 6 (MCM6) (AA 562-821) antibody
MCM6 Reaktivität: Human WB, IF, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 6 (MCM6) antibodyKD Validated MCM6 Reaktivität: Human WB, FACS, IF (p) Wirt: Kaninchen Monoclonal 23GB2005 unconjugated Recombinant Antibody
anti-Minichromosome Maintenance Complex Component 6 (MCM6) (AA 1-821) antibodyMCM6 Reaktivität: Human WB, IF, IHC (p), PLA Wirt: Maus Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 6 (MCM6) (AA 228-368) antibodyMCM6 Reaktivität: Human IHC, StM Wirt: Maus Monoclonal MCM6-2999 unconjugated
anti-Minichromosome Maintenance Complex Component 6 (MCM6) (AA 1-821) antibodyMCM6 Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 7D8 unconjugated
anti-Minichromosome Maintenance Complex Component 6 (MCM6) (AA 589-605), (Middle Region) antibodyMCM6 Reaktivität: Human, Maus, Ratte IHC, WB, IF, ICC, FACS, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 6 (MCM6) (AA 562-821) antibodyMCM6 Reaktivität: Human IHC, WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 6 (MCM6) antibodyMCM6 Reaktivität: Human, Maus, Ratte IHC, WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 6 (MCM6) (AA 670-792) antibodyMCM6 Reaktivität: Human WB, BI Wirt: Maus Monoclonal 1-MCM6 unconjugated
anti-Minichromosome Maintenance Complex Component 6 (MCM6) (C-Term) antibodyMCM6 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen IHC, WB Wirt: Kaninchen Polyclonal unconjugated
-
-
Applikationshinweise
- IHC 1:50-1:200 IF 1:50-1:200
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
-
Konservierungsmittel
- Sodium azide
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))
-
Andere Bezeichnung
- MCM6
-
Hintergrund
- The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication. Single nucleotide polymorphisms in the intron regions of this gene are associated with differential transcriptional activation of the promoter of the neighboring lactase gene and, thereby, influence lactose intolerance in early adulthood.
-
Molekulargewicht
-
Observed_MW: 110kDa
Calculated_MW: 92kDa
-
Gen-ID
- 4175
-
UniProt
- Q14566
-
Pathways
- DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
Target
-
