PPP2R4 Antikörper (Protein Phosphatase 2A Activator, Regulatory Subunit 4)

Details for Product anti-PPP2R4 Antibody No. ABIN6568975
Target
Reaktivität
Human, Maus, Ratte
63
26
23
3
2
2
2
2
2
2
2
2
1
1
Wirt
Kaninchen
53
11
1
Klonalität
Polyklonal
Konjugat
Dieser PPP2R4 Antikörper ist unkonjugiert
4
4
2
2
2
2
2
2
2
1
1
1
1
1
Applikation
Immunofluorescence (IF), Immunohistochemistry (IHC)
49
23
18
6
6
6
3
3
3
2
2
1
1
1
Optionen
Immunogen Recombinant protein of human PPP2R4
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung PPP2R4 (PPP2R4 Antibody Abstract)
Hintergrund

Synonyms: subunit B'',KIAA0044 ,MGC2184 ,Phosphotyrosyl phosphatase activator,PP2A,PP2A phosphatase activator ,PP2A subunit B',PP2A subunit B' isoform PR53,PP2A subunit B' PR53 isoform ,PPP2R4,PR53 ,PR53 isoform,Protein phosphatase 2, regulatory subunit B-prime,Protein phosphatase 2A activator regulatory subunit 4,Protein phosphatase 2A regulatory subunit B' (PR 53),PTPA,PTPA,Serine/threonine protein phosphatase 2A regulatory subunit B' ,Serine/threonine-protein phosphatase 2A activator,Serine/threonine-protein phosphatase 2A regulatory subunit 4,Serine/threonine-protein phosphatase 2A regulatory subunit B''

Background: Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molekulargewicht

Calculated_MW: 31kDa/33kDa/36kDa/40kDa

Gen-ID 5524
UniProt Q15257
Pathways PI3K-Akt Signalweg, M Phase, Hepatitis C, Toll-Like Receptors Cascades
Applikations-hinweise IHC 1:50 - 1:200 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) antibody (ABIN6568975) Immunohistochemistry of paraffin-embedded rat brain using PPP2R4 Antibody.
Image no. 2 for anti-Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) antibody (ABIN6568975) Immunohistochemistry of paraffin-embedded human kidney cancer using PPP2R4 Antibody.
Image no. 3 for anti-Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) antibody (ABIN6568975) Immunofluorescence analysis of U2OS cells using PPP2R4 antibody.