IFI16 Antikörper (Interferon, gamma-Inducible Protein 16)

Details for Product anti-IFI16 Antibody No. ABIN6568235
Target
Reaktivität
Human, Maus, Ratte
44
3
Wirt
Kaninchen
36
8
Klonalität
Polyklonal
Konjugat
Dieser IFI16 Antikörper ist unkonjugiert
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
30
16
13
8
8
6
3
1
1
1
1
Optionen
Immunogen Recombinant protein of human IFI16
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung IFI16 (IFI16 Antibody Abstract)
Hintergrund

Synonyms: IFI16,Gamma interferon inducible protein 16,Gamma-interferon-inducible protein Ifi16,IF16,Ifi204,IFNGIP1,interferon activated gene 204,Interferon gamma induced protein IFI 16,Interferon gamma inducible protein 16,Interferon-inducible myeloid differentiation transcriptional activator,p204,PYHIN2

Background: This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht

Observed_MW: 88kDa

Calculated_MW: 75kDa/82kDa/88kDa

Gen-ID 3428
UniProt Q16666
Pathways Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Autophagie
Applikations-hinweise WB 1:500 - 1:2000 IHC 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Interferon, gamma-Inducible Protein 16 (IFI16) antibody (ABIN6568235) Western blot analysis of extracts of various cell lines, using IFI16 antibody.
Image no. 2 for anti-Interferon, gamma-Inducible Protein 16 (IFI16) antibody (ABIN6568235) Immunohistochemistry of paraffin-embedded rat liver using IFI16 Antibody.
Image no. 3 for anti-Interferon, gamma-Inducible Protein 16 (IFI16) antibody (ABIN6568235) Immunohistochemistry of paraffin-embedded mouse lung using IFI16 Antibody.
Image no. 4 for anti-Interferon, gamma-Inducible Protein 16 (IFI16) antibody (ABIN6568235) Immunohistochemistry of paraffin-embedded mouse liver using IFI16 Antibody.