RIN2 Antikörper

Produktnummer ABIN6568165

Dieses Anti-RIN2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RIN2 in WB. Geeignet für Human und Maus.

Kurzübersicht für RIN2 Antikörper (ABIN6568165)

Target: RIN2 (Ras and Rab Interactor 2 (RIN2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RIN2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RIN2 Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human RIN2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu RIN2

Target: RIN2 (Ras and Rab Interactor 2 (RIN2))

Andere Bezeichnung: RIN2

Hintergrund:

Synonyms: MACS ,RAB5 interacting protein 2,Ras and Rab interactor 2,RAS association (RalGDS/AF-6) domain containing protein JC265,Ras association domain family 4,Ras inhibitor JC265,Ras interaction/interference protein 2,RASSF4,RIN 2,RIN2,RIN2

Background: The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants.

Molekulargewicht:

Observed_MW: 120kDa

Calculated_MW: 100kDa/105kDa

Gen-ID: 54453

UniProt: Q8WYP3