RIN2 Antikörper (AA 596-895)
Kurzübersicht für RIN2 Antikörper (AA 596-895) (ABIN6146954)
Target
Alle RIN2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 596-895
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Sequenz
- HKCILKPLKG HVEAMLKDFH MADGSWKQLK ENLQLVRQRN PQELGVFAPT PDFVDVEKIK VKFMTMQKMY SPEKKVMLLL RVCKLIYTVM ENNSGRMYGA DDFLPVLTYV IAQCDMLELD TEIEYMMELL DPSLLHGEGG YYLTSAYGAL SLIKNFQEEQ AARLLSSETR DTLRQWHKRR TTNRTIPSVD DFQNYLRVAF QEVNSGCTGK TLLVRPYITT EDVCQICAEK FKVGDPEEYS LFLFVDETWQ QLAEDTYPQK IKAELHSRPQ PHIFHFVYKR IKNDPYGIIF QNGEEDLTTS
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Kreuzreaktivität
- Human, Maus
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 596-895 of human RIN2 (NP_061866.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- RIN2 (Ras and Rab Interactor 2 (RIN2))
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Andere Bezeichnung
- RIN2
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Hintergrund
- The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants.,RIN2,MACS,RASSF4,Signal Transduction,G protein signaling,Signal Transduction,RIN2
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Molekulargewicht
- 100 kDa/105 kDa
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Gen-ID
- 54453
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UniProt
- Q8WYP3
Target
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