RIN2 Antikörper (N-Term)

Produktnummer ABIN2790373

Der Kaninchen Polyklonal anti-RIN2 Antikörper (ABIN2790373) detektiert spezifisch RIN2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Rind (Kuh), Pferd, Schwein, Ratte und Hund.

Kurzübersicht für RIN2 Antikörper (N-Term) (ABIN2790373)

Target: RIN2 (Ras and Rab Interactor 2 (RIN2))

Reaktivität: Human, Maus, Rind (Kuh), Pferd, Schwein, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RIN2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RIN2 Antikörper

Bindungsspezifität: N-Term

Sequenz: RTDVNLENGL EPAETHSMVR HKDGGYSEEE DVKTCARDSG YDSLSNRLSI

Homologie: Cow: 80%, Dog: 80%, Horse: 80%, Human: 100%, Mouse: 83%, Pig: 80%, Rat: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against RIN2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human RIN2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RIN2

Target: RIN2 (Ras and Rab Interactor 2 (RIN2))

Andere Bezeichnung: RIN2

Hintergrund: The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants.
Alias Symbols: MACS, RASSF4
Protein Size: 462

Molekulargewicht: 50 kDa

Gen-ID: 54453

NCBI Accession: NM_001242581, NP_001229510

UniProt: Q8WYP3