ATP2A2 Antikörper (ATPase, Ca++ Transporting, Cardiac Muscle, Slow Twitch 2)

Details for Product anti-ATP2A2 Antibody No. ABIN6567041
Target
Reaktivität
Human, Maus, Ratte
54
31
30
7
5
4
4
4
4
3
3
2
2
2
2
1
1
1
1
Wirt
Kaninchen
54
1
1
Klonalität
Polyklonal
Konjugat
Dieser ATP2A2 Antikörper ist unkonjugiert
5
3
3
2
2
2
2
2
2
2
2
2
Applikation
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
43
27
11
10
3
2
2
1
1
Optionen
Immunogen Recombinant protein of human ATP2A2
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung ATP2A2 (ATP2A2 Antibody Abstract)
Hintergrund

Synonyms: AT2A2,Atp2a2,ATP2B,ATPase Ca++ transporting cardiac muscle slow twitch 2,Calcium pump 2,Calcium-transporting ATPase sarcoplasmic reticulum type,Calcium-transporting ATPase sarcoplasmic reticulum type slow twitch skeletal muscle isoform,Cardiac Ca2+ ATPase,DAR,DD,Endoplasmic reticulum class 1/2 Ca(2+) ATPase,MGC45367,Sarcoplasmic/endoplasmic reticulum calcium ATPase 2,SERCA 2,SERCA2,serca2a,slow twitch skeletal muscle isoform,SR Ca(2+)-ATPase 2

Background: This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molekulargewicht

Observed_MW: 115kDa

Calculated_MW: 109kDa/111kDa/114kDa

Gen-ID 488
UniProt P16615
Pathways Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Ribonucleoside Biosynthetic Process
Applikations-hinweise WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:10 - 1:100
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-ATPase, Ca++ Transporting, Cardiac Muscle, Slow Twitch 2 (ATP2A2) antibody (ABIN6567041) Immunofluorescence analysis of HeLa cells using ATP2A2 antibody.
Image no. 2 for anti-ATPase, Ca++ Transporting, Cardiac Muscle, Slow Twitch 2 (ATP2A2) antibody (ABIN6567041) Western blot analysis of extracts of various cell lines, using ATP2A2 antibody.
Image no. 3 for anti-ATPase, Ca++ Transporting, Cardiac Muscle, Slow Twitch 2 (ATP2A2) antibody (ABIN6567041) Immunohistochemistry of paraffin-embedded rat brain using ATP2A2 Antibody.