Nascent Polypeptide Associated Complex alpha 1 (NACa1) Antikörper

Details zu Produkt Nr. ABIN6566781
Target
Reaktivität
Human, Maus, Ratte
26
21
20
Wirt
Kaninchen
24
2
Klonalität
Polyklonal
Konjugat
Unkonjugiert
2
2
2
2
2
2
2
Applikation
Western Blotting (WB)
14
8
4
2
2
2
Optionen
Immunogen Recombinant protein of human NACA
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung NACA (NACa1 Antibody Abstract)
Hintergrund

Synonyms: Alpha NAC,Alpha-NAC,Hom s 2.02,HSD48 ,MGC117224,NAC-alpha,naca,NACA/1.9.2,NACA,NACA1,Nascent polypeptide associated complex alpha polypeptide,Nascent polypeptide associated complex alpha subunit,Nascent polypeptide associated complex subunit alpha,Nascent polypeptide-associated complex subunit alpha

Background: This gene encodes a protein that associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC). This complex binds to nascent proteins that lack a signal peptide motif as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum. This protein is an IgE autoantigen in atopic dermatitis patients. Alternative splicing results in multiple transcript variants, but the full length nature of some of these variants, including those encoding very large proteins, has not been determined. There are multiple pseudogenes of this gene on different chromosomes.

Molekulargewicht

Observed_MW: 37kDa, 39kDa

Calculated_MW: 23kDa/94kDa/205kDa

Gen-ID 4666
UniProt Q13765
Pathways Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Applikations-hinweise WB 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Nascent Polypeptide Associated Complex alpha 1 (NACa1) antibody (ABIN6566781) Western blot analysis of extracts of various cell lines, using NACA antibody.