NACA Antikörper (pSer43)

Produktnummer ABIN1450497

Der Kaninchen Polyklonal anti-NACA Antikörper (ABIN1450497) detektiert spezifisch NACA in IHC, ELISA und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für NACA Antikörper (pSer43) (ABIN1450497)

Target: NACA (NACa1) (Nascent Polypeptide Associated Complex alpha 1 (NACa1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NACA Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-NACA Antikörper

Bindungsspezifität: AA 9-58, pSer43

Verwendungszweck: NACA (phospho Ser43) Antibody

Spezifität: Phospho-NACA (S43) Polyclonal Antibody detects endogenous levels of NACA protein only when phosphorylated at S43.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human NACA around the phosphorylation site of Ser43. AA range:9-58

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu NACA

Target: NACA (NACa1) (Nascent Polypeptide Associated Complex alpha 1 (NACa1))

Andere Bezeichnung: NACA

Hintergrund:

Synonyms: NACA, HSD48, Nascent polypeptide-associated complex subunit alpha, NAC-alpha, Alpha-NAC, allergen Hom s 2

Background: This gene encodes a protein that associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC). This complex binds to nascent proteins that lack a signal peptide motif as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum. This protein is an IgE autoantigen in atopic dermatitis patients. Alternative splicing results in multiple transcript variants, but the full length nature of some of these variants, including those encoding very large proteins, has not been determined. There are multiple pseudogenes of this gene on different chromosomes. [provided by RefSeq, Feb 2016],

Gene Name: NACA

Protein Name: Nascent polypeptide-associated complex subunit alpha

Molekulargewicht: 23 kDa

Gen-ID: 4666

OMIM: 601234

UniProt: Q13765

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development