NACA Antikörper (N-Term)

Produktnummer ABIN6263507

Produktdetails anti-NACA Antikörper

Target: NACA (NACa1) (Nascent Polypeptide Associated Complex alpha 1 (NACa1))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NACA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: NACA Antibody detects endogenous levels of total NACA.

Homologie: Pig,Bovine,Sheep,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human NACA, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu NACA

Target: NACA (NACa1) (Nascent Polypeptide Associated Complex alpha 1 (NACa1))

Andere Bezeichnung: NACA (NACa1 Produkte)

Synonyme: AL022831 antikoerper, AL024382 antikoerper, Gm1878 antikoerper, mKIAA0363 antikoerper, skNAC antikoerper, ik:tdsubc_2b5 antikoerper, nkn antikoerper, tdsubc_2b5 antikoerper, xx:tdsubc_2b5 antikoerper, NACA1 antikoerper, nascent polypeptide-associated complex alpha polypeptide antikoerper, nascent polypeptide-associated complex alpha subunit antikoerper, Naca antikoerper, naca antikoerper, NACA antikoerper

Hintergrund:

Description: Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites). May act as a specific coactivator for JUN, binding to DNA and stabilizing the interaction of JUN homodimers with target gene promoters.

Gene: NACA

Molekulargewicht: 24kDa

Gen-ID: 4666

UniProt: Q13765

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development