NACA Antikörper

Produktnummer ABIN6566781

Der Kaninchen Polyklonal Anti-NACA-Antikörper wurde für WB validiert. Er ist geeignet, NACA in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für NACA Antikörper (ABIN6566781)

Target: NACA (NACa1) (Nascent Polypeptide Associated Complex alpha 1 (NACa1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NACA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NACA Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human NACA

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu NACA

Target: NACA (NACa1) (Nascent Polypeptide Associated Complex alpha 1 (NACa1))

Andere Bezeichnung: NACA

Hintergrund:

Synonyms: Alpha NAC,Alpha-NAC,Hom s 2.02,HSD48 ,MGC117224,NAC-alpha,naca,NACA/1.9.2,NACA,NACA1,Nascent polypeptide associated complex alpha polypeptide,Nascent polypeptide associated complex alpha subunit,Nascent polypeptide associated complex subunit alpha,Nascent polypeptide-associated complex subunit alpha

Background: This gene encodes a protein that associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC). This complex binds to nascent proteins that lack a signal peptide motif as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum. This protein is an IgE autoantigen in atopic dermatitis patients. Alternative splicing results in multiple transcript variants, but the full length nature of some of these variants, including those encoding very large proteins, has not been determined. There are multiple pseudogenes of this gene on different chromosomes.

Molekulargewicht:

Observed_MW: 37kDa, 39kDa

Calculated_MW: 23kDa/94kDa/205kDa

Gen-ID: 4666

UniProt: Q13765

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development