BAK1 Antikörper
Kurzübersicht für BAK1 Antikörper (ABIN6566497)
Target
Alle BAK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Affinity purification
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Immunogen
- A synthetic peptide of human BAK1 (NP_001179.1).
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:2000 IF 1:50-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Konservierungsmittel
- Sodium azide
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- BAK1 (BCL2-Antagonist/killer 1 (BAK1))
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Andere Bezeichnung
- BAK1
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Hintergrund
- The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
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Molekulargewicht
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Observed_MW: 26kDa
Calculated_MW: 16kDa/23kDa
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Gen-ID
- 578
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UniProt
- Q16611
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Pathways
- Apoptose, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
Target
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