Complement Factor H Antikörper (AA 751-780)

Produktnummer ABIN2844545

Der Kaninchen Polyklonal anti-Complement Factor H Antikörper wird verwendet zum Nachweis von Complement Factor H in Proben von Human. Er wurde validiert für WB, IF und IHC (p).

Kurzübersicht für Complement Factor H Antikörper (AA 751-780) (ABIN2844545)

Target: Complement Factor H (CFH)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Complement Factor H Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB18698

Produktdetails anti-Complement Factor H Antikörper

Bindungsspezifität: AA 751-780

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CFH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 751-780 amino acids of human CFH.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF: 1:25. IF: 1:25. WB: 1:2000. WB: 1:2000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu Complement Factor H

Target: Complement Factor H (CFH)

Andere Bezeichnung: CFH

Hintergrund: This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Molekulargewicht: 139096

Gen-ID: 3075

NCBI Accession: NP_000177

UniProt: P08603

Pathways: Komplementsystem, Cellular Response to Molecule of Bacterial Origin