NSUN2 Antikörper (AA 423-451)

Produktnummer ABIN654767

Der Kaninchen Polyklonal Anti-NSUN2-Antikörper wurde für WB validiert. Er ist geeignet, NSUN2 in Proben von Human und Maus zu detektieren.

Kurzübersicht für NSUN2 Antikörper (AA 423-451) (ABIN654767)

Target: NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NSUN2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB28701

Produktdetails anti-NSUN2 Antikörper

Bindungsspezifität: AA 423-451

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NSUN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 423-451 amino acids from the Central region of human NSUN2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu NSUN2

Target: NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))

Andere Bezeichnung: NSUN2

Hintergrund: Maturation of cytoplasmic tRNAs includes splicing of introns, which are located 1 nucleotide 3-prime from the anticodon in all intron-containing tRNA genes. In tRNA-leu(CAA), the first position of the anticodon, C34, is converted to 5-methylcytosine, a modification necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. NSUN2 encodes a methyltransferase that catalyzes the intron-dependent formation of 5-methylcytosine at C34 of tRNA-leu(CAA) (Brzezicha et al., 2006 [PubMed 17071714]).

Molekulargewicht: 86471

Gen-ID: 54888

NCBI Accession: NP_001180384, NP_060225

UniProt: Q08J23