Hepcidin Antikörper (AA 17-46)

Produktnummer ABIN653413

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Hepcidin in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Hepcidin Antikörper (AA 17-46) (ABIN653413)

Target: Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Hepcidin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB22098

Produktdetails anti-Hepcidin Antikörper

Bindungsspezifität: AA 17-46

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HAMP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-46 amino acids from the Central region of human HAMP.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:500. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu Hepcidin

Target: Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Andere Bezeichnung: HAMP

Hintergrund: HAMP is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity.

Molekulargewicht: 9408

Gen-ID: 57817

NCBI Accession: NP_066998

UniProt: P81172

Pathways: Hormone Activity, Transition Metal Ion Homeostasis