Src Antikörper (pTyr419)

Produktnummer ABIN650803

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Src in DB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Src Antikörper (pTyr419) (ABIN650803)

Target: Src (Proto-oncogene tyrosine-protein kinase Src (Src))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Src Antikörper ist unkonjugiert

Applikation: Dot Blot (DB)

Klon: RB21491

Produktdetails anti-Src Antikörper

Bindungsspezifität: pTyr419

Homologie: Zf, B, C, M, Pig, Rat, X

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SRC Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y419 of human SRC.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: DB: 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu Src

Target: Src (Proto-oncogene tyrosine-protein kinase Src (Src))

Andere Bezeichnung: SRC

Hintergrund: This proto-oncogene may play a role in the regulation of embryonic development and cell growth. This protein is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase.

Molekulargewicht: 59835

Gen-ID: 6714

NCBI Accession: NP_005408, NP_938033

UniProt: P12931

Pathways: JAK-STAT Signalweg, Neurotrophin Signalübertragung, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagie, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling