Connexin 43/GJA1 Antikörper

Produktnummer ABIN641009

Der Kaninchen Polyklonal Anti-Connexin 43/GJA1-Antikörper wurde für WB, ELISA und Func validiert. Er ist geeignet, Connexin 43/GJA1 in Proben von Huhn zu detektieren.

Kurzübersicht für Connexin 43/GJA1 Antikörper (ABIN641009)

Target: Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

Reaktivität: Huhn

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Connexin 43/GJA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Functional Studies (Func)

Produktdetails anti-Connexin 43/GJA1 Antikörper

Verwendungszweck: Rabbit Anti-Chicken Connexin 43 (pSer368)

Spezifität: This product recognizes chicken Interferon gamma (chIFN-gamma). Original studies investigating the properties of chicken Interferon (chIFN), revealed properties similar to mammalian IFN type I (IFNI), and it has since become apparent that there are at least three distinct chicken interferon proteins, designated as chIFN-alpha, chIFN-beta and chIFN-gamma. chIFN-gamma was first identified, when supernatant from chicken spleen cells stimulated with concanavalin A (ConA ), displayed macrophage-activating factor (MAF) activity - the principle function of mammalian type II IFN-gamma. Several independent studies have since supported the existence of this chicken homolog, by the cloning of IFN-gamma cDNA from activated chicken T cells and demonstrating that recombinant chicken IFN-gamma strongly upregulates the expression of MHC class II and iNOS genes. It can be used to neutralize chIFN-gamma activity and to discriminate the antiviral activity of chIFN-gamma from that of chIFN-alpha and chIFN-beta (2).

Produktmerkmale: Adhesion Molecule/Cell Surface

Immunogen: Antisera to chicken Interferon Gamma were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography on protein G.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA, Functional Assays, Western Blotting

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: IgG concentration 0.5 mg/ml

Buffer: Phosphate buffered saline

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Details zu Connexin 43/GJA1

Target: Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

Andere Bezeichnung: Connexin 43

Pathways: MAPK Signalweg, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization