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Connexin 43/GJA1 Antikörper (AA 351-367)

GJA1 Reaktivität: Human, Ratte, Maus WB, IHC (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3031019
  • Target Alle Connexin 43/GJA1 (GJA1) Antikörper anzeigen
    Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))
    Bindungsspezifität
    • 21
    • 16
    • 15
    • 12
    • 8
    • 7
    • 7
    • 7
    • 7
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 351-367
    Reaktivität
    • 136
    • 94
    • 92
    • 35
    • 13
    • 12
    • 12
    • 10
    • 10
    • 8
    • 7
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 129
    • 10
    • 4
    • 1
    Kaninchen
    Klonalität
    • 133
    • 10
    Polyklonal
    Konjugat
    • 84
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Connexin 43/GJA1 Antikörper ist unkonjugiert
    Applikation
    • 99
    • 54
    • 48
    • 28
    • 23
    • 16
    • 13
    • 13
    • 13
    • 8
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Aufreinigung
    Antigen affinity
    Immunogen
    Amino acids 351-367 (HELQPLAIVDQRPSSRA-human) were used as the immunogen for this Cx43 antibody (100% conserved in mouse and rat).
    Isotyp
    IgG
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  • Applikationshinweise
    Titration of the Cx43 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Lagerung
    -20 °C
    Informationen zur Lagerung
    The lyophilized Cx43 antibody can be stored at 4°C to -20°C. After reconstitution, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))
    Andere Bezeichnung
    Cx43 Connexin 43 (GJA1 Produkte)
    Synonyme
    AVSD3 antikoerper, CX43 antikoerper, DFNB38 antikoerper, GJAL antikoerper, HLHS1 antikoerper, HSS antikoerper, ODDD antikoerper, Cx43 antikoerper, AU042049 antikoerper, AW546267 antikoerper, Cnx43 antikoerper, Cx43alpha1 antikoerper, Gja-1 antikoerper, Npm1 antikoerper, connexin43 antikoerper, cx43a1 antikoerper, gja1 antikoerper, zfCx43.3 antikoerper, connexin 43 antikoerper, gja1-A antikoerper, cx43 antikoerper, gjal antikoerper, oddd antikoerper, dfnb38 antikoerper, gap junction protein alpha 1 antikoerper, gap junction protein, alpha 1 antikoerper, connexin 43 antikoerper, gap junction protein alpha 1 L homeolog antikoerper, CONNEXIN 43 protein antikoerper, GJA1 antikoerper, Gja1 antikoerper, cx43 antikoerper, gja1.L antikoerper, gja1 antikoerper, CONNEXIN 43 antikoerper
    Hintergrund
    Connexin 43 (Cx43), also called GAP Junction Protein, alpha, is a member of the connexin gene family and is abundantly expressed in the heart and liver. Connexin 43, the major protein of gap junctions in the heart, is targeted by several protein kinases that regulate myocardial cell-cell coupling. Cx43 also plays a critical role in the physiology of hearing, presumably by participating in the recycling of potassium to the cochlear endolymph.
    UniProt
    P17302
    Pathways
    MAPK Signalweg, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization
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