IFNA Antikörper
Kurzübersicht für IFNA Antikörper (ABIN639854)
Target
Alle IFNA Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- Mouse Anti-Chicken IFN-alpha
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Spezifität
- DS-MB-01578 recognizes chicken Interferon alpha (chIFN-alpha). The classification of mammalian cytokines with antiviral activity, is well documented as being either Type I Interferon (IFN I) or Type II Interferon (IFN II). This is not the case for avian IFNs however, even though IFN was first detected in the chicken. A growing number of functional studies indicate similarities between chicken IFN and mammalian IFNI, revealing the conservation of cysteine residues and the existence of around ten closely related intron-less IFN alpha genes. Further research has shown that chIFN-alpha genes are strongly expressed following viral infection of monocyte-derived macrophage and embryo fibroblasts and that recombinant chicken IFN acts as a potent antiviral agent. DS-MB-01578 does not cross react with IFN beta or IFN gamma and does not neutralize chIFN-alpha.
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Produktmerkmale
- Cytokines/Chemokines/Growth Factors/Receptors
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Aufreinigung
- Purified
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Immunogen
- Recombinant chicken Interferon alpha
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Isotyp
- IgG1
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Applikationshinweise
- ELISA, Western Blotting
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- IgG concentration 0.5 mg/ml
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Buffer
- Phosphate buffered saline
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C
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- IFNA (Interferon alpha (IFNA))
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Andere Bezeichnung
- Interferon-alpha (IFNa)
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Pathways
- JAK-STAT Signalweg, TLR Signalweg, Hepatitis C, Inflammasome
Target
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