DMBT1 Antikörper

Produktnummer ABIN6390433

Dieses Anti-DMBT1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DMBT1 in IHC (p). Geeignet für Human, Maus und Ratte.

Kurzübersicht für DMBT1 Antikörper (ABIN6390433)

Target: DMBT1 (Deleted in Malignant Brain Tumors 1 (DMBT1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DMBT1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-DMBT1 Antikörper

Verwendungszweck: Unconjugated Rabbit polyclonal to DMBT1

Spezifität: DMBT1 Polyclonal Antibody detects endogenous levels of protein.

Aufreinigung: DMBT1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-p 1:50-300

Kommentare:

Highly expressed in alveolar and macrophage tissues. In some macrophages, expression is seen on the membrane, and in other macrophages, strongly expressed in the phagosome/phagolysosome compartments. Expressed in lung, trachea, salivary gland, small intestine and stomach. In pancreas, expressed in certain cells of the islets of Langerhans. In digestive tract, confined to tissues with large epithelial surfaces. In intestinal tissue, moderately expressed in epithelial cells of the midcrypts and the crypt base. Expression is significantly elevated in intestinal tissue from patients with inflammatory bowel disease (IBD), particularly in surface epithelial and Paneth cells, but not in IBD patients with mutant NOD2. Present in crypt bases of the duodenum, in crypt tops of the colon, and in collecting ducts of the cortical kidney. Expressed in stratified squamous epithelium of vagina and in outer luminar surface and basilar region of columnar epithelial cells in cervix (at protein level). Isoform 1 is secreted to the lumen of the respiratory tract.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid form in PBS containing 50 % glycerol,and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C, and avoid repeat freeze-thaw cycles.

Details zu DMBT1

Target: DMBT1 (Deleted in Malignant Brain Tumors 1 (DMBT1))

Andere Bezeichnung: DMBT1

Molekulargewicht: 265 kDa

Gen-ID: 1755

UniProt: Q9UGM3

Pathways: Activation of Innate immune Response