GDNF Antikörper (AA 100-180)
Kurzübersicht für GDNF Antikörper (AA 100-180) (ABIN6390139)
Target
Alle GDNF Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 100-180
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Verwendungszweck
- Unconjugated Rabbit polyclonal to GDNF
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Spezifität
- GDNF Polyclonal Antibody detects endogenous levels of protein.
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Aufreinigung
- GDNF antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized peptide derived from human GDNF protein.
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-2000 ELISA 1:5000-20000
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Kommentare
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In the brain, predominantly expressed in the striatum with highest levels in the caudate and lowest in the putamen. Isoform 2 is absent from most tissues except for low levels in intestine and kidney. Highest expression of isoform 3 is found in pancreatic islets. Isoform 5 is expressed at very low levels in putamen, nucleus accumbens, prefrontal cortex, amygdala, hypothalamus and intestine. Isoform 3 is up-regulated in the middle temporal gyrus of Alzheimer disease patients while isoform 2 shows no change.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid form in PBS containing 50 % glycerol,and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))
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Andere Bezeichnung
- GDNF
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Molekulargewicht
- 23 kDa
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Gen-ID
- 2668
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UniProt
- P39905
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Pathways
- RTK Signalweg, Synaptic Membrane, Tube Formation, Autophagie, Smooth Muscle Cell Migration
Target
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