AMACR Antikörper (AA 33-48)
Kurzübersicht für AMACR Antikörper (AA 33-48) (ABIN636371)
Target
Alle AMACR Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 33-48
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Aufreinigung
- Affinity chromatography purified
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Immunogen
- AMACR antibody was raised in rabbit using AA 33-48 [RVDRPGSRYDVSRLGR] of the 42 kDa human AMACR (P504 S) protein as the immunogen.
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:100, WB: 1:500. For IHC, an incubation period of 30 minutes at room temperature is suggested. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining.
Optimal conditions should be determined by the investigator. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- Lot specific
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Buffer
- Affinity purified and supplied in PBS, with 0.02 % NaN3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Handhabung
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
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- AMACR (alpha-Methylacyl-CoA Racemase (AMACR))
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Andere Bezeichnung
- AMACR
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Hintergrund
- Alpha-methylacyl-CoA racemase (AMACR), (also known as P504S) is an enzyme that is involved in peroxisomal beta-oxidation of dietary branched-chain fatty acids. Recent studies have shown that, compared with expression in normal or benign prostate epithelium, AMACR is consistently overexpressed in prostate cancer epithelium, making it a specific marker for cancer cells within the prostate gland.
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Pathways
- Monocarboxylic Acid Catabolic Process
Target
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