ORAI1 Antikörper (N-Term)

Produktnummer ABIN635032

Produktdetails anti-ORAI1 Antikörper

Target: ORAI1 (ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ORAI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: ORAI1 antibody was raised against the N terminal of ORAI1

Aufreinigung: Affinity purified

Immunogen: ORAI1 antibody was raised using the N terminal of ORAI1 corresponding to a region with amino acids HPEPAPPPSRSSPELPPSGGSTTSGSRRSRRRSGDGEPPGAPPPPPSAVT

Anwendungsinformationen

Applikationshinweise: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

ORAI1 Blocking Peptide, catalog no. 33R-3809, is also available for use as a blocking control in assays to test for specificity of this ORAI1 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of ORAI1 antibody in PBS

Konzentration: Lot specific

Buffer: PBS

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Details zu ORAI1

Target: ORAI1 (ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))

Andere Bezeichnung: ORAI1 (ORAI1 Produkte)

Hintergrund: ORAI1 belongs to the Orai family. ORAI1 (CRACM1) is a plasma membrane protein essential for store-operated calcium entry. Defects in ORAI1 are a cause of severe combined immunodeficiency with CRAC channel dysfunction.

Molekulargewicht: 33 kDa (MW of target protein)

Pathways: T-Zell Rezeptor Signalweg, BCR Signaling