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MCM6 Antikörper (C-Term)

MCM6 Reaktivität: Human, Hund WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN630187
  • Target Alle MCM6 Antikörper anzeigen
    MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))
    Bindungsspezifität
    • 12
    • 9
    • 8
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 57
    • 23
    • 17
    • 9
    • 7
    • 7
    • 7
    • 4
    • 2
    • 1
    • 1
    Human, Hund
    Wirt
    • 47
    • 6
    • 4
    Kaninchen
    Klonalität
    • 52
    • 5
    Polyklonal
    Konjugat
    • 40
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MCM6 Antikörper ist unkonjugiert
    Applikation
    • 44
    • 33
    • 20
    • 15
    • 11
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Spezifität
    MCM6 antibody was raised against the C terminal of MCM6
    Aufreinigung
    Purified
    Immunogen
    MCM6 antibody was raised using the C terminal of MCM6 corresponding to a region with amino acids RIIEKVIHRLTHYDHVLIELTQAGLKGSTEGSESYEEDPYLVVNPNYLLE
    Top Product
    Discover our top product MCM6 Primärantikörper
  • Applikationshinweise
    WB: 1.25 µg/mL, IHC: 4-8 µg/mL
    Optimal conditions should be determined by the investigator.
    Kommentare

    MCM6 Blocking Peptide, catalog no. 33R-7967, is also available for use as a blocking control in assays to test for specificity of this MCM6 antibody

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of MCM6 antibody in PBS
    Konzentration
    Lot specific
    Buffer
    PBS
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Target
    MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))
    Andere Bezeichnung
    MCM6 (MCM6 Produkte)
    Synonyme
    CG4039 antikoerper, DmMCM6 antikoerper, DmeMCM6 antikoerper, Dmel\\CG4039 antikoerper, MCM6 antikoerper, McM6 antikoerper, fs(1)K1214 antikoerper, mcm6 antikoerper, MCG40308 antikoerper, Mis5 antikoerper, P105MCM antikoerper, Mcmd6 antikoerper, mis5 antikoerper, mmcm6 antikoerper, ASP-l1 antikoerper, D1Wsu22e antikoerper, Minichromosome maintenance 6 antikoerper, DNA replication licensing factor MCM6 antikoerper, minichromosome maintenance complex component 6 antikoerper, minichromosome maintenance complex component 6 L homeolog antikoerper, DNA replication licensing factor mcm-6 antikoerper, Mcm6 antikoerper, TP02_0113 antikoerper, PVX_114735 antikoerper, CMU_027970 antikoerper, MCM6 antikoerper, mcm6.L antikoerper, mcm-6 antikoerper
    Hintergrund
    The protein encoded by the MCM6 gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.
    Molekulargewicht
    90 kDa (MW of target protein)
    Pathways
    DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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