CD25 Antikörper
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- Target Alle CD25 (IL2RA) Antikörper anzeigen
- CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD25 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)
- Verwendungszweck
- Mouse anti-Human CD25 Antibody [Sodium Azide Free]
- Spezifität
- Cell surface
- Aufreinigung
- Stimulated human leukocytes were used as the immunogen for the CD25 antibody.
- Immunogen
- Stimulated human leukocytes were used as the immunogen for the CD25 antibody.
- Top Product
- Discover our top product IL2RA Primärantikörper
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- Applikationshinweise
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Functional Activity (Order SAF formulation)
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- In 1X PBS, BSA free, sodium azide free
- Konservierungsmittel
- Azide free
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Target
- CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
- Andere Bezeichnung
- Interleukin-2 receptor subunit alpha (IL2RA Produkte)
- Synonyme
- CD25 antikoerper, IDDM10 antikoerper, IL2R antikoerper, TCGFR antikoerper, IL2RAC antikoerper, IL-2RA antikoerper, Il2r antikoerper, Ly-43 antikoerper, interleukin 2 receptor subunit alpha antikoerper, interleukin-2 receptor subunit alpha-like antikoerper, interleukin 2 receptor, alpha chain antikoerper, IL2RA antikoerper, Il2ra antikoerper, LOC100222957 antikoerper
- Hintergrund
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Target Description: Recognizes a protein of 55 kDa, identified as CD25 (Workshop IV, Code A27). CD25 is expressed on activated T- and B-cells and activated monocytes/macrophages. With respect to lymphomas, CD25 is present on malignant cells of Hodgkins disease, HTLV-1+ adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 Molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R b-chain, p75) and CD132 (common g-chain) to form the high affinity IL-2 receptor complex. CD25 antibodies detect three epitope regions, A, B and C. This mAb recognizes the epitope B, which is located at residue 3-104 of CD25 and can effectively block IL-2 binding to CD25.
Gene Symbol: IL2RA
- Gen-ID
- 3559
- UniProt
- P01589
- Pathways
- JAK-STAT Signalweg, Growth Factor Binding, Activated T Cell Proliferation
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