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CD25 Antikörper

Dieser Anti-CD25-Antikörper ist ein Maus-Monoklonal-Antikörper zum Nachweis von CD25 in FACS, IF und Func. Geeignet für Human.
Produktnummer ABIN6297678
714,43 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach: Deutschland
Lieferung in 10 bis 13 Werktagen

Kurzübersicht für CD25 Antikörper (ABIN6297678)

Target

Alle CD25 (IL2RA) Antikörper anzeigen
CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

Reaktivität

  • 257
  • 147
  • 43
  • 11
  • 10
  • 5
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
Human

Wirt

  • 197
  • 110
  • 98
  • 20
  • 2
  • 2
  • 2
  • 1
Maus

Klonalität

  • 351
  • 76
  • 4
Monoklonal

Konjugat

  • 161
  • 43
  • 34
  • 31
  • 28
  • 11
  • 8
  • 7
  • 7
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CD25 Antikörper ist unkonjugiert

Applikation

  • 266
  • 98
  • 88
  • 60
  • 59
  • 58
  • 32
  • 25
  • 18
  • 16
  • 10
  • 9
  • 9
  • 8
  • 8
  • 6
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)
  • Verwendungszweck

    Mouse anti-Human CD25 Antibody [Sodium Azide Free]

    Spezifität

    Cell surface

    Aufreinigung

    Stimulated human leukocytes were used as the immunogen for the CD25 antibody.

    Immunogen

    Stimulated human leukocytes were used as the immunogen for the CD25 antibody.
  • Applikationshinweise

    Functional Activity (Order SAF formulation)
    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 0.5-1 μg/mL

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    In 1X PBS, BSA free, sodium azide free

    Konservierungsmittel

    Azide free

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • Target

    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

    Andere Bezeichnung

    Interleukin-2 receptor subunit alpha

    Hintergrund

    Target Description: Recognizes a protein of 55 kDa, identified as CD25 (Workshop IV, Code A27). CD25 is expressed on activated T- and B-cells and activated monocytes/macrophages. With respect to lymphomas, CD25 is present on malignant cells of Hodgkins disease, HTLV-1+ adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 Molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R b-chain, p75) and CD132 (common g-chain) to form the high affinity IL-2 receptor complex. CD25 antibodies detect three epitope regions, A, B and C. This mAb recognizes the epitope B, which is located at residue 3-104 of CD25 and can effectively block IL-2 binding to CD25.

    Gene Symbol: IL2RA

    Gen-ID

    3559

    UniProt

    P01589

    Pathways

    JAK-STAT Signalweg, Growth Factor Binding, Activated T Cell Proliferation
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