XRCC6 Antikörper

Produktnummer ABIN6296746

Dieses Maus Monoklonal-Antikörper erkennt spezifisch XRCC6 in IF, FACS und ICC. Er zeigt eine Reaktivität gegenüber Human und Primate.

Kurzübersicht für XRCC6 Antikörper (ABIN6296746)

Target: XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))

Reaktivität: Human, Primate

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser XRCC6 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Produktdetails anti-XRCC6 Antikörper

Verwendungszweck: Mouse anti-Human/Primates Ku70 + Ku80 Antibody [Sodium Azide Free]

Spezifität: Nuclear

Aufreinigung: Nuclear extract of human HL-60 cells was used as the immunogen for this Ku70 + Ku80 antibody.

Immunogen: Nuclear extract of human HL-60 cells was used as the immunogen for this Ku70 + Ku80 antibody.

Anwendungsinformationen

Applikationshinweise: Flow cytometry: 0.5-1 μg/10e6 cells
IF: 0.5-1.0 μg/mL
Immunocytochemistry (Acetone-fixed cells): 0.25-0.5 μg/mL for 30 minutes at RT

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu XRCC6

Target: XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))

Andere Bezeichnung: X-ray repair cross-complementing protein 6

Hintergrund:

Target Description: This antibody recognizes a dimer of two proteins of 70 kDa (Ku70) and ~80 kDa (Ku80), identified as two subunits of Ku. Antbody KU729 recognizes a conformational epitope of the Ku70 + Ku80 dimer, which is destroyed during Western blotting. The Ku70 + Ku80 dimer is important for function of a 460 kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.

Gene Symbol: XRCC6///G22P1

Gen-ID: 2547

UniProt: P12956

Pathways: DNA Reparatur