Keratin 77 Antikörper

Produktnummer ABIN6296178

Dieses Anti-Keratin 77-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Keratin 77 in IHC, WB und IF. Geeignet für Human und Ratte.

Kurzübersicht für Keratin 77 Antikörper (ABIN6296178)

Target: Keratin 77 (KRT77)

Reaktivität: Human, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Keratin 77 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-Keratin 77 Antikörper

Verwendungszweck: Mouse anti-Human/Rat Acidic Cytokeratin Antibody [Sodium Azide Free]

Spezifität: Cytoplasmic

Aufreinigung: An amino acid sequence common to acidic/type I keratins was used as the immunogen for the Acidic Cytokeratin antibody.

Immunogen: An amino acid sequence common to acidic/type I keratins was used as the immunogen for the Acidic Cytokeratin antibody.

Anwendungsinformationen

Applikationshinweise: Western blot: 1-2 μg/mL (3)
Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu Keratin 77

Target: Keratin 77 (KRT77)

Andere Bezeichnung: Keratin, type II cytoskeletal 1b

Hintergrund:

Target Description: There are two types of cytokeratins/keratins/CKs: the acidic type I cytokeratins and the basic or neutral type II cytokeratins. The subsets of cytokeratins which an epithelial cell expresses depends mainly on the type of epithelium, the moment in the course of terminal differentiation and the stage of development. Thus this specific keratin fingerprint allows the classification of all epithelia upon their keratin expression profile. Furthermore this applies also to the malignant counterparts of the epithelia (carcinomas), as the keratin profile tends to remain constant when an epithelium undergoes malignant transformation. The main clinical implication is that the study of the keratin profile by immunohistochemistry techniques is a tool of immense value widely used for tumor diagnosis and characterization in surgical pathology. [Wiki]

Gene Symbol: KRT77///KRT1B

Gen-ID: 374454

UniProt: Q7Z794