Keratin 77 Antikörper

Produktnummer ABIN6296176

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Keratin 77 in IHC, WB, IF und FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Keratin 77 Antikörper (ABIN6296176)

Target: Keratin 77 (KRT77)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Keratin 77 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-Keratin 77 Antikörper

Verwendungszweck: Rabbit anti-Human Recombinant Acidic Cytokeratin Antibody [Sodium Azide Free]

Spezifität: Cytoplasmic

Aufreinigung: An amino acid sequence common to acidic/type I keratins (1) was used as the immunogen for the recombinant Acidic Cytokeratin antibody.

Immunogen: An amino acid sequence common to acidic/type I keratins (1) was used as the immunogen for the recombinant Acidic Cytokeratin antibody.

Anwendungsinformationen

Applikationshinweise: Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT (3)
Prediluted IHC only format: incubate for 30 min at RT (2)
FACS: 0.5-1 μg/million cells in 0.1ml
WB: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu Keratin 77

Target: Keratin 77 (KRT77)

Andere Bezeichnung: Keratin, type II cytoskeletal 1b

Hintergrund:

Target Description: There are two types of cytokeratins/keratins/CKs: the acidic type I cytokeratins and the basic or neutral type II cytokeratins. The subsets of cytokeratins which an epithelial cell expresses depends mainly on the type of epithelium, the moment in the course of terminal differentiation and the stage of development. Thus this specific keratin fingerprint allows the classification of all epithelia upon their keratin expression profile. Furthermore this applies also to the malignant counterparts of the epithelia (carcinomas), as the keratin profile tends to remain constant when an epithelium undergoes malignant transformation. The main clinical implication is that the study of the keratin profile by immunohistochemistry techniques is a tool of immense value widely used for tumor diagnosis and characterization in surgical pathology. [Wiki]

Gene Symbol: KRT77///KRT1B

Gen-ID: 374454

UniProt: Q7Z794