BAX Antikörper
Kurzübersicht für BAX Antikörper (ABIN6296161)
Target
Alle BAX Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- Mouse anti-human/monkey Bax Antibody [Sodium Azide Free]
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Spezifität
- Cytoplasmic
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Aufreinigung
- Amino acids GSGEQPRGGGPTSS (3-16) were used as the immunogen for this anti-human Bax antibody.
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Immunogen
- Amino acids GSGEQPRGGGPTSS (3-16) were used as the immunogen for this anti-human Bax antibody.
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Applikationshinweise
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ELISA: order BSA-free format for coating
FACS: 0.5-1 μg/million cells
IF: 1-2 μg/mL
WB: 0.5-1 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2) -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- In 1X PBS ( pH 7.4), BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- BAX (BCL2-Associated X Protein (BAX))
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Andere Bezeichnung
- Apoptosis regulator BAX
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Hintergrund
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Target Description: This antibody recognizes a protein of 21 kDa, identified as the Bax protein. The Bax antibody is highly specific and shows no cross-reaction with Bcl-2 alpha or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and the protein also counters the death repressor activity of Bcl-2.
Gene Symbol: BAX///BCL2L4
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Gen-ID
- 581
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UniProt
- Q07812
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Pathways
- p53 Signalweg, PI3K-Akt Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
Target
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