Calnexin Antikörper

Produktnummer ABIN6296055

Dieses Anti-Calnexin-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Calnexin in WB, IHC, IF und FACS. Geeignet für Human.

Kurzübersicht für Calnexin Antikörper (ABIN6296055)

Target: Calnexin (CANX)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Calnexin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-Calnexin Antikörper

Verwendungszweck: Mouse anti-Human Calnexin Antibody [Sodium Azide Free]

Spezifität: Cytoplasmic

Aufreinigung: A partial human recombinant protein was used as the immunogen for the Calnexin antibody.

Immunogen: A partial human recombinant protein was used as the immunogen for the Calnexin antibody.

Anwendungsinformationen

Applikationshinweise: WB: 0.5-1 μg/mL
FACS: 0.5-1 μg/10^6 cells
Immunofluorescence: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu Calnexin

Target: Calnexin (CANX)

Andere Bezeichnung: Calnexin  

Hintergrund:

Target Description: It recognizes a protein of 90 kDa, which is identified as Calnexin. Secretory and transmembrane proteins are synthesized on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including calnexin. It is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.

Gene Symbol: CANX

Gen-ID: 821

UniProt: P27824

Pathways: MAPK Signalweg, Thyroid Hormone Synthesis