XRCC6 Antikörper
Kurzübersicht für XRCC6 Antikörper (ABIN6295976)
Target
Alle XRCC6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- Mouse anti-Human Ku70 + Ku80 Antibody [Sodium Azide Free]
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Spezifität
- Nuclear
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Aufreinigung
- A human cell nuclear fraction was used as the immunogen for this Ku70 + Ku80 antibody.
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Immunogen
- A human cell nuclear fraction was used as the immunogen for this Ku70 + Ku80 antibody.
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Applikationshinweise
- Flow cytometry: 0.5-1 μg/10e6 cells
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- In 1X PBS ( pH 7.4), BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))
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Andere Bezeichnung
- X-ray repair cross-complementing protein 6
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Hintergrund
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Target Description: Together, Ku70 and Ku80 make up the Ku heterodimer, which binds to DNA double-strand break ends and is required for the non-homologous end joining (NHEJ) pathway of DNA repair. It is also required for V(D)J recombination, which utilizes the NHEJ pathway to promote antigen diversity in the mammalian immune system. In addition to its role in NHEJ, Ku is also required for telomere length maintenance and subtelomeric gene silencing. Ku was originally identified when patients with systemic lupus erythematosus were found to have high levels of autoantibodies to the protein. [Wiki]
Gene Symbol: XRCC6///G22P1
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Gen-ID
- 2547
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UniProt
- P12956
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Pathways
- DNA Reparatur
Target
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