XRCC6 Antikörper

Produktnummer ABIN6295976

Der Maus Monoklonal Anti-XRCC6 Antikörper wurde für FACS validiert. Er ist geeignet, XRCC6 in Proben von Human zu detektieren.

Kurzübersicht für XRCC6 Antikörper (ABIN6295976)

Target: XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser XRCC6 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Produktdetails anti-XRCC6 Antikörper

Verwendungszweck: Mouse anti-Human Ku70 + Ku80 Antibody [Sodium Azide Free]

Spezifität: Nuclear

Aufreinigung: A human cell nuclear fraction was used as the immunogen for this Ku70 + Ku80 antibody.

Immunogen: A human cell nuclear fraction was used as the immunogen for this Ku70 + Ku80 antibody.

Anwendungsinformationen

Applikationshinweise: Flow cytometry: 0.5-1 μg/10e6 cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu XRCC6

Target: XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))

Andere Bezeichnung: X-ray repair cross-complementing protein 6

Hintergrund:

Target Description: Together, Ku70 and Ku80 make up the Ku heterodimer, which binds to DNA double-strand break ends and is required for the non-homologous end joining (NHEJ) pathway of DNA repair. It is also required for V(D)J recombination, which utilizes the NHEJ pathway to promote antigen diversity in the mammalian immune system. In addition to its role in NHEJ, Ku is also required for telomere length maintenance and subtelomeric gene silencing. Ku was originally identified when patients with systemic lupus erythematosus were found to have high levels of autoantibodies to the protein. [Wiki]

Gene Symbol: XRCC6///G22P1

Gen-ID: 2547

UniProt: P12956

Pathways: DNA Reparatur