Tyrosinase-Related Protein 1 Antikörper

Produktnummer ABIN6295921

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Tyrosinase-Related Protein 1 in IHC, IF und FACS. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für Tyrosinase-Related Protein 1 Antikörper (ABIN6295921)

Target: Tyrosinase-Related Protein 1 (TYRP1)

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Tyrosinase-Related Protein 1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-Tyrosinase-Related Protein 1 Antikörper

Verwendungszweck: Mouse anti-Human/Mouse TRP1 Antibody [Sodium Azide Free]

Spezifität: Cytoplasmic

Aufreinigung: Recombinant full-length human protein was used as the immunogen for the TRP1 antibody.

Immunogen: Recombinant full-length human protein was used as the immunogen for the TRP1 antibody.

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (FFPE): 2-4 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu Tyrosinase-Related Protein 1

Target: Tyrosinase-Related Protein 1 (TYRP1)

Andere Bezeichnung: 5,6-dihydroxyindole-2-carboxylic acid oxidase

Hintergrund:

Target Description: It reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.

Gene Symbol: TYRP1///CAS2///TYRP///TYRRP

Gen-ID: 7306

UniProt: P17643