BAX Antikörper (AA 3-16)
Kurzübersicht für BAX Antikörper (AA 3-16) (ABIN6294454)
Target
Alle BAX Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 3-16
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Verwendungszweck
- Mouse anti-Human/Monkey Bax Antibody [Sodium Azide Free]
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Spezifität
- Cytoplasmic
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Aufreinigung
- Amino acids 3-16 (GSGEQPRGGGPTSS) from the human protein were used as the immunogen for this anti-Bax antibody.
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Immunogen
- Amino acids 3-16 (GSGEQPRGGGPTSS) from the human protein were used as the immunogen for this anti-Bax antibody.
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Applikationshinweise
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Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Western blot: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2) -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- In 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- BAX (BCL2-Associated X Protein (BAX))
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Andere Bezeichnung
- Apoptosis regulator BAX
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Hintergrund
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Target Description: Recognizes a protein of 21 kDa, identified as the Bax protein. This mAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.
Gene Symbol: BAX///BCL2L4
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Gen-ID
- 581
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UniProt
- Q07812
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Pathways
- p53 Signalweg, PI3K-Akt Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
Target
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