E2F1 Antikörper (C-Term)
Kurzübersicht für E2F1 Antikörper (C-Term) (ABIN6266337)
Target
Alle E2F1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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    - 
                                            Bindungsspezifität
- C-Term
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                                            Spezifität
- E2F1 Antibody detects endogenous levels of total E2F1.
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                                            Homologie
- Pig,Bovine,Horse,Rabbit
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                                            Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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                                            Immunogen
- A synthesized peptide derived from human E2F1, corresponding to a region within C-terminal amino acids.
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                                            Isotyp
- IgG
 
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- 
    - 
                                            Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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    - 
                                            Format
- Liquid
- 
                                            Konzentration
- 1 mg/mL
- 
                                            Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 
                                            Konservierungsmittel
- Sodium azide
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                                            Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 
                                            Lagerung
- -20 °C
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                                            Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- 
                                            Haltbarkeit
- 12 months
 
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    - E2F1 (E2F Transcription Factor 1 (E2F1))
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                                            Andere Bezeichnung
- E2F1
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                                            Hintergrund
- 
                        Description: Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis. Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA binding to its target gene promoters (PubMed:20176812). Positively regulates transcription of RRP1B (PubMed:20040599). Gene: E2F1 
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                                            Molekulargewicht
- 47kDa
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                                            Gen-ID
- 1869
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                                            UniProt
- Q01094
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                                            Pathways
- p53 Signalweg, Zellzyklus, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Autophagie
 Target
- 
                    
 
                                     
                                     
                                    