MCM6 Antikörper (C-Term)

Produktnummer ABIN6263166

Produktdetails anti-MCM6 Antikörper

Target: MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MCM6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Spezifität: MCM6 Antibody detects endogenous levels of total MCM6.

Homologie: Pig,Horse,Sheep,Rabbit

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MCM6, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu MCM6

Target: MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))

Andere Bezeichnung: MCM6 (MCM6 Produkte)

Synonyme: CG4039 antikoerper, DmMCM6 antikoerper, DmeMCM6 antikoerper, Dmel\\CG4039 antikoerper, MCM6 antikoerper, McM6 antikoerper, fs(1)K1214 antikoerper, mcm6 antikoerper, MCG40308 antikoerper, Mis5 antikoerper, P105MCM antikoerper, Mcmd6 antikoerper, mis5 antikoerper, mmcm6 antikoerper, ASP-l1 antikoerper, D1Wsu22e antikoerper, Minichromosome maintenance 6 antikoerper, DNA replication licensing factor MCM6 antikoerper, minichromosome maintenance complex component 6 antikoerper, minichromosome maintenance complex component 6 L homeolog antikoerper, DNA replication licensing factor mcm-6 antikoerper, Mcm6 antikoerper, TP02_0113 antikoerper, PVX_114735 antikoerper, CMU_027970 antikoerper, MCM6 antikoerper, mcm6.L antikoerper, mcm-6 antikoerper

Hintergrund:

Description: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.

Gene: MCM6

Molekulargewicht: 93kDa

Gen-ID: 4175

UniProt: Q14566

Pathways: DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA