IL-6 Receptor Antikörper (N-Term)
Kurzübersicht für IL-6 Receptor Antikörper (N-Term) (ABIN6262530)
Target
Alle IL-6 Receptor (IL6R) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- N-Term
-
Spezifität
- IL6R Antibody detects endogenous levels of total IL6R.
-
Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
-
Immunogen
- A synthesized peptide derived from human IL6R, corresponding to a region within N-terminal amino acids.
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
-
Haltbarkeit
- 12 months
-
-
- IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))
-
Andere Bezeichnung
- IL6R
-
Hintergrund
-
Description: Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis.
Gene: IL6R
-
Molekulargewicht
- 52kD
-
Gen-ID
- 3570
-
UniProt
- P08887
-
Pathways
- JAK-STAT Signalweg, Autophagie, Growth Factor Binding, Cancer Immune Checkpoints
Target
-