GATA4 Antikörper (pSer262)
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- Target Alle GATA4 Antikörper anzeigen
- GATA4 (GATA Binding Protein 4 (GATA4))
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Bindungsspezifität
- pSer262
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Reaktivität
- Human, Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GATA4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- Phospho-GATA4 (Ser262) Antibody detects endogenous levels of GATA4 only when phosphorylated at Serine 262.
- Homologie
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Aufreinigung
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
- Immunogen
- A synthesized peptide derived from human GATA4 around the phosphorylation site of Ser262.
- Isotyp
- IgG
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anti-GATA Binding Protein 4 (GATA4) (pSer105) antibody
GATA4 Reaktivität: Human, Ratte, Maus WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-GATA Binding Protein 4 (GATA4) antibodyGATA4 Reaktivität: Human WB, IHC Wirt: Kaninchen Monoclonal unconjugated
anti-GATA Binding Protein 4 (GATA4) (AA 228-440) antibodyGATA4 Reaktivität: Ratte WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-GATA Binding Protein 4 (GATA4) (AA 50-150) antibodyGATA4 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-GATA Binding Protein 4 (GATA4) (AA 201-442) antibodyGATA4 Reaktivität: Human WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-GATA Binding Protein 4 (GATA4) (AA 261-360) antibodyGATA4 Reaktivität: Human, Ratte, Maus WB, ELISA, IHC (p), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated
anti-GATA Binding Protein 4 (GATA4) (AA 298-328), (C-Term) antibodyGATA4 Reaktivität: Human WB, FACS Wirt: Kaninchen Polyclonal RB13444 unconjugated
anti-GATA Binding Protein 4 (GATA4) (AA 330-380) antibodyGATA4 Reaktivität: Human WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-GATA Binding Protein 4 (GATA4) antibodyGATA4 Reaktivität: Human, Maus WB, BI Wirt: Maus Monoclonal L97-56 unconjugated
anti-GATA Binding Protein 4 (GATA4) (AA 343-442) antibodyGATA4 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 6C6 unconjugated
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- Applikationshinweise
- WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- GATA4 (GATA Binding Protein 4 (GATA4))
- Andere Bezeichnung
- GATA4 (GATA4 Produkte)
- Hintergrund
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Description: Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development and function (PubMed:24000169, PubMed:27984724). In cooperation with TBX5, it binds to cardiac super-enhancers and promotes cardiomyocyte gene expression, while it downregulates endocardial and endothelial gene expression (PubMed:27984724). Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions (By similarity). Acts as a transcriptional activator of ANF in cooperation with NKX2-5 (By similarity). Promotes cardiac myocyte enlargement (PubMed:20081228). Required during testicular development (PubMed:21220346). May play a role in sphingolipid signaling by regulating the expression of sphingosine-1-phosphate degrading enzyme, spingosine-1-phosphate lyase (PubMed:15734735).
Gene: GATA4
- Molekulargewicht
- 48kDa
- Gen-ID
- 2626
- UniProt
- P43694
- Pathways
- Peptide Hormone Metabolism, Carbohydrate Homeostasis
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