MECP2 Antikörper (pSer80)
Kurzübersicht für MECP2 Antikörper (pSer80) (ABIN6255514)
Target
Alle MECP2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer80
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Spezifität
- Phospho-MeCP2(Ser80) Antibody detects endogenous levels of MeCP2.
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Kreuzreaktivität
- Human, Maus, Ratte (Rattus)
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Aufreinigung
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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Immunogen
- A synthesized peptide derived from human MeCP2 around the phosphorylation site of Ser80.
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Isotyp
- IgG
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anti-Methyl CpG Binding Protein 2 (MECP2) (AA 7-148) antibody
MECP2 Reaktivität: Human WB, IHC, ELISA, ICC, FACS Wirt: Maus Monoclonal 8H4A5B9 unconjugated
anti-Methyl CpG Binding Protein 2 (MECP2) (AA 81-170) antibodyMECP2 Reaktivität: Human WB, ELISA, IHC (p) Wirt: Maus Monoclonal 1B11 unconjugated
anti-Methyl CpG Binding Protein 2 (MECP2) (pSer423) antibodyMECP2 Reaktivität: Human, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal RB29261 unconjugated
anti-Methyl CpG Binding Protein 2 (MECP2) (AA 1-486) antibodyMECP2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Methyl CpG Binding Protein 2 (MECP2) (AA 400-428) antibodyMECP2 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB25959 unconjugated
anti-Methyl CpG Binding Protein 2 (MECP2) (C-Term) antibodyMECP2 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Methyl CpG Binding Protein 2 (MECP2) (AA 58-87), (N-Term) antibodyMECP2 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB27934 unconjugated
anti-Methyl CpG Binding Protein 2 (MECP2) (AA 81-170) antibodyMECP2 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IHC (p) Wirt: Maus Monoclonal 4B6 unconjugated
anti-Methyl CpG Binding Protein 2 (MECP2) (N-Term) antibodyMECP2 Reaktivität: Human, Maus, Ratte WB, ELISA, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Methyl CpG Binding Protein 2 (MECP2) (pSer80) antibodyMECP2 Reaktivität: Human DB Wirt: Kaninchen Polyclonal RB27934 unconjugated
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Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
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Haltbarkeit
- 12 months
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- MECP2 (Methyl CpG Binding Protein 2 (MECP2))
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Andere Bezeichnung
- MeCP2
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Hintergrund
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Description: Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).
Gene: MECP2
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Molekulargewicht
- 75kDa
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Gen-ID
- 4204
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UniProt
- P51608
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Pathways
- Inositol Metabolic Process, Chromatin Binding, Synaptic Membrane
Target
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