Calnexin Antikörper (pSer564)
Kurzübersicht für Calnexin Antikörper (pSer564) (ABIN6255414)
Target
Alle Calnexin (CANX) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- pSer564
-
Spezifität
- Phospho-Calnexin(Ser564) Antibody detects endogenous levels of Calnexin.
-
Kreuzreaktivität
- Human, Maus, Ratte (Rattus)
-
Aufreinigung
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
-
Immunogen
- A synthesized peptide derived from human Calnexin around the phosphorylation site of Ser564.
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
-
Haltbarkeit
- 12 months
-
-
- Calnexin (CANX)
-
Andere Bezeichnung
- Calnexin
-
Hintergrund
-
Description: Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse.
Gene: CANX
-
Molekulargewicht
- 90kDa
-
Gen-ID
- 821
-
UniProt
- P27824
-
Pathways
- MAPK Signalweg, Thyroid Hormone Synthesis
Target
-