SREBF1 Antikörper (pSer439)
Kurzübersicht für SREBF1 Antikörper (pSer439) (ABIN6255339)
Target
Alle SREBF1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- pSer439
-
Spezifität
- Phospho-SREBP1 (Ser439) Antibody detects endogenous levels of SREBP1 only when phosphorylated at Serine 439.
-
Homologie
- Pig,Horse,Sheep,Dog
-
Aufreinigung
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
-
Immunogen
- A synthesized peptide derived from human SREBP1 around the phosphorylation site of Ser439.
-
Isotyp
- IgG
-
-
anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (AA 38-201) antibody
SREBF1 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (AA 349-378) antibodySREBF1 Reaktivität: Human WB, IHC (p), FACS Wirt: Kaninchen Polyclonal RB21265 unconjugated
anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (AA 801-900) antibodySREBF1 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 4B10 unconjugated
anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (AA 1-100) antibodySREBF1 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (Middle Region) antibodySREBF1 Reaktivität: Human, Ratte, Maus, Rind (Kuh), Ziege, Pferd WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (AA 158-390) antibodySREBF1 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (AA 461-510) antibodySREBF1 Reaktivität: Human, Ratte, Rind (Kuh), Ziege, Pferd, Hamster WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (Middle Region) antibodySREBF1 Reaktivität: Human, Ratte, Maus, Schwein, Rind (Kuh) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) antibodySREBF1 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (AA 250-330) antibodySREBF1 Reaktivität: Human, Ratte, Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
-
-
Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
-
Haltbarkeit
- 12 months
-
-
- SREBF1 (Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))
-
Andere Bezeichnung
- SREBF1
-
Hintergrund
-
Description: Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway (By similarity). Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'). Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3').
Gene: SREBF1
-
Molekulargewicht
- 122kDa
-
Gen-ID
- 6720
-
UniProt
- P36956
-
Pathways
- AMPK Signaling, Caspase Kaskade in der Apoptose, Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha
Target
-
