CDC25B Antikörper (pSer353)
Kurzübersicht für CDC25B Antikörper (pSer353) (ABIN6255250)
Target
Alle CDC25B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer353
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Spezifität
- Phospho-CDC25B (Ser353) Antibody detects endogenous levels of CDC25B only when phosphorylated at Serine 353
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Kreuzreaktivität
- Human, Maus
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Aufreinigung
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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Immunogen
- A synthesized peptide derived from human CDC25B around the phosphorylation site of Serine 353
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
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Haltbarkeit
- 12 months
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- CDC25B (Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B))
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Andere Bezeichnung
- CDC25B
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Hintergrund
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Description: Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity.
Gene: CDC25B
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Molekulargewicht
- 64kDa
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Gen-ID
- 994
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UniProt
- P30305
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Pathways
- Zellzyklus, M Phase, Autophagie
Target
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