MECP2 Antikörper (pSer421)

Produktnummer ABIN6254071

Dieser Anti-MECP2 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von MECP2 in WB und ELISA. Geeignet für Maus. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für MECP2 Antikörper (pSer421) (ABIN6254071)

Target: MECP2 (Methyl CpG Binding Protein 2 (MECP2))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MECP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-MECP2 Antikörper

Bindungsspezifität: pSer421

Spezifität: Specific for endogenous levels of the ~55 kDa truncated MeCP2 protein phosphorylated at Ser421. Immunolabeling is blocked by preadsorption with the phosphopeptide used as antigen, but not by the corresponding non-phosphopeptide.

Kreuzreaktivität: Maus, Ratte

Homologie: human, non-human primate

Produktmerkmale: Our MeCP2 (Ser421) rabbit polyclonal phosphospecific primary antibody is produced in-house. It detects MeCP2 (Ser421) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.

Aufreinigung: Prepared from pooled rabbit serum by affinity purification via sequential chromatography on phospho and non-phosphopeptide affinity columns.

Immunogen: Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser421 of mouse MeCP2, conjugated to keyhole limpet hemocyanin (KLH).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Dilution Range: WB Brain: 1:1000

Dilution Range: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Lagerung: -20 °C

Informationen zur Lagerung: Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Haltbarkeit: 12 months

Referenzen für anti-MECP2 Antikörper (ABIN6254071)

Buck, ONeill, Stitzel et al.: "Developmental nicotine exposure engenders intergenerational downregulation and aberrant posttranslational modification of cardinal epigenetic factors in the frontal cortices, striata, and hippocampi ..." in: Epigenetics & chromatin, Vol. 13, Issue 1, pp. 13, (2020) (PubMed).

Details zu MECP2

Target: MECP2 (Methyl CpG Binding Protein 2 (MECP2))

Andere Bezeichnung: MECP2

Hintergrund:

Synonyms: AUTSX 3 antibody, AUTSX3 antibody, DKFZp686A24160 antibody, Mbd 5 antibody, Mbd5 antibody, MECP 2 antibody, MeCP 2 protein antibody, MeCP-2 protein antibody, Mecp2 antibody, MECP2_HUMAN antibody, Methyl CpG binding protein 2 (Rett syndrome) antibody, Methyl CpG binding protein 2 antibody, Methyl-CpG-binding protein 2 antibody, MRX 16 antibody, MRX 79 antibody, MRX16 antibody, MRX79 antibody, MRXS 13 antibody, MRXS13 antibody, MRXSL antibody, PPMX antibody, RS antibody, RTS antibody, RTT antibody, WBP 10 antibody, WBP10 antibody

Description Logic: Our MeCP2 (Ser421) rabbit polyclonal phosphospecific primary antibody is produced . It detects MeCP2 (Ser421) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.

Gene Name Alternatives: MECP2

Molekulargewicht: 55 kDa

Gen-ID: 17257

UniProt: Q9Z2D6

Pathways: Inositol Metabolic Process, Chromatin Binding, Synaptic Membrane