MALT1 Antikörper (AA 701-808)
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- Target Alle MALT1 Antikörper anzeigen
- MALT1 (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1))
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Bindungsspezifität
- AA 701-808
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser MALT1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)
- Aufreinigung
- Protein G purified
- Immunogen
- A recombinant fragment (aa 701-808) was used as the immunogen for this antibody.
- Klon
- 4NMT-3
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product MALT1 Primärantikörper
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- Applikationshinweise
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IF: 1-2 μg/mL
WB: 0.5-1 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format : incubate for 30 min at RT (2)
Titering of the MALT1 antibody may be required for optimal performance.1. FFPE testing requires sections to be boiled in pH 6 10 mM citrate buffer for 10-20 minutes, followed by cooling at RT for 20 minutes, prior to staining.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.2 mg/mL
- Buffer
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- Target
- MALT1 (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1))
- Andere Bezeichnung
- MALT1 (MALT1 Produkte)
- Synonyme
- malt1 antikoerper, MALT1 antikoerper, mlt antikoerper, mlt1 antikoerper, MLT antikoerper, MLT1 antikoerper, A630046N12 antikoerper, D430033E09Rik antikoerper, MALT paracaspase 2 antikoerper, MALT1 paracaspase antikoerper, MALT1 paracaspase S homeolog antikoerper, paracaspase 3 antikoerper, malt2 antikoerper, MALT1 antikoerper, malt1.S antikoerper, Malt1 antikoerper, PCASP3 antikoerper
- Hintergrund
- Mucosa associated lymphoid tissue lymphoma translocation gene 1 is found in extranodal low-grade B cell lymphomas. It encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of the MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition.
- Gen-ID
- 10892
- UniProt
- Q9UDY8
- Pathways
- T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteine
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