PRKACB Antikörper (N-Term)

Produktnummer ABIN6243845

Produktdetails anti-PRKACB Antikörper

Target: PRKACB (Protein Kinase, CAMP Dependent, Catalytic, beta (PRKACB))

Bindungsspezifität: AA 14-43, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRKACB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PKA C-beta (PRKACB) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-43 amino acids from the N-terminal region of human PKA C-beta (PRKACB).

Klon: RB3546

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu PRKACB

Target: PRKACB (Protein Kinase, CAMP Dependent, Catalytic, beta (PRKACB))

Andere Bezeichnung: PKA C-beta (PRKACB) (PRKACB Produkte)

Synonyme: PKACB antikoerper, XPKAbeta antikoerper, kin-1 antikoerper, pkacb antikoerper, prkacba antikoerper, PRKACB antikoerper, prkacb antikoerper, wu:fz54b03 antikoerper, zgc:110804 antikoerper, Pkacb antikoerper, protein kinase cAMP-activated catalytic subunit beta antikoerper, protein kinase cAMP-activated catalytic subunit beta S homeolog antikoerper, protein kinase, cAMP-dependent, catalytic, beta antikoerper, protein kinase, cAMP-dependent, catalytic, beta b antikoerper, protein kinase, cAMP dependent, catalytic, beta antikoerper, PRKACB antikoerper, prkacb.S antikoerper, prkacb antikoerper, Prkacb antikoerper, prkacbb antikoerper

Hintergrund: CAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase (AMPK), which transduces the signal through phosphorylation of different target proteins. The inactive holoenzyme of AMPK is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits of AMPK have been identified in humans. PRKACB is a member of the Ser/Thr protein kinase family and is a catalytic subunit of AMPK.

Molekulargewicht: 40623

NCBI Accession: NP_001229786, NP_001229787, NP_001229788, NP_001229789, NP_001229790, NP_001229791, NP_002722, NP_891993, NP_997461

UniProt: P22694

Pathways: AMPK Signaling, Hedgehog Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Lipid Metabolism