Caspase 3 Antikörper (N-Term)
Kurzübersicht für Caspase 3 Antikörper (N-Term) (ABIN6243633)
Target
Alle Caspase 3 (CASP3) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1-30, N-Term
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Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This mouse CASP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of mouse CASP3.
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Isotyp
- Ig Fraction
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anti-Caspase 3 (CASP3) (AA 60-100) antibody
CASP3 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Ziege WB, IF (cc) Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase 3 (CASP3) (AA 67-175) antibodyCASP3 Reaktivität: Human, Maus, Ratte WB, IHC, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase 3 (CASP3) (AA 220-236), (C-Term) antibodyCASP3 Reaktivität: Human WB, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase 3 (CASP3) antibodyCASP3 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Maus Monoclonal 5E1 unconjugated
anti-Caspase 3 (CASP3) (AA 11-120) antibodyCASP3 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase 3 (CASP3) (cleaved) antibodyCASP3 Reaktivität: Human, Maus, Ratte IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase 3 (CASP3) (Internal Region) antibodyCASP3 Reaktivität: Human, Maus, Ratte, Rind (Kuh) WB, IHC, ELISA, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase 3 (CASP3) (pSer150) antibodyCASP3 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase 3 (CASP3) (AA 29-175) antibodyCASP3 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase 3 (CASP3) (AA 29-175) antibodyCASP3 Reaktivität: Human WB, IHC, IP, ICC Wirt: Maus Monoclonal C3 unconjugated
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Applikationshinweise
- WB: 1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Haltbarkeit
- 6 months
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- Caspase 3 (CASP3)
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Andere Bezeichnung
- CASP3
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Hintergrund
- CASP3 is involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9 (By similarity). Cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes.
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Molekulargewicht
- 31475
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NCBI Accession
- NP_033940
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UniProt
- P70677
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Pathways
- Apoptose, Caspase Kaskade in der Apoptose, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
Target
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