TLR2 Antikörper

Produktnummer ABIN6243378

Der Maus Monoklonal Anti-TLR2-Antikörper wurde für WB validiert. Er ist geeignet, TLR2 in Proben von Human zu detektieren.

Kurzübersicht für TLR2 Antikörper (ABIN6243378)

Target: TLR2 (Toll-Like Receptor 2 (TLR2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TLR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 1070CT4-2-3-2

Produktdetails anti-TLR2 Antikörper

Aufreinigung: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This TLR2 Antibody is generated from a mouse immunized with a recombinant protein .

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu TLR2

Target: TLR2 (Toll-Like Receptor 2 (TLR2))

Andere Bezeichnung: TLR2

Hintergrund: Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6.

Molekulargewicht: 89838

UniProt: O60603

Pathways: TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades