SQSTM1 Antikörper (Ser351)
Kurzübersicht für SQSTM1 Antikörper (Ser351) (ABIN6242568)
Target
Alle SQSTM1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 346-379, Ser351
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Homologie
- Rat
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Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This Phospho-Sqstm1(S351) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 346-379 amino acids from the human region of human Phospho-Sqstm1(S351).
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Isotyp
- Ig Fraction
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anti-Sequestosome 1 (SQSTM1) (AA 317-346) antibody
SQSTM1 Reaktivität: Human, Maus WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB4614 unconjugated
anti-Sequestosome 1 (SQSTM1) antibodyKO Validated SQSTM1 Reaktivität: Human WB, IF, ICC, IP, FACS, IHC (p), PLA Wirt: Kaninchen Polyclonal unconjugated
anti-Sequestosome 1 (SQSTM1) (AA 1-440) antibodySQSTM1 Reaktivität: Human WB, IHC, IF, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Sequestosome 1 (SQSTM1) (AA 51-150) antibodySQSTM1 Reaktivität: Human, Maus, Ratte, Rind (Kuh) WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Sequestosome 1 (SQSTM1) (AA 232-356) antibodySQSTM1 Reaktivität: Human WB, IHC, ELISA, FACS Wirt: Maus Monoclonal 5H7E2 unconjugated
anti-Sequestosome 1 (SQSTM1) (AA 1-440) antibodySQSTM1 Reaktivität: Human WB, IF, ELISA Wirt: Maus Monoclonal 2C11 unconjugated
anti-Sequestosome 1 (SQSTM1) (AA 136-400) antibodySQSTM1 Reaktivität: Human WB, IHC, ICC, IP, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Sequestosome 1 (SQSTM1) (C-Term) antibodySQSTM1 Reaktivität: Human, Maus, Ratte WB, IHC, IF, ICC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Sequestosome 1 (SQSTM1) antibodySQSTM1 Reaktivität: Human, Affe WB, IHC, IF, FACS, IHC (p) Wirt: Maus Monoclonal 5A2 unconjugated
anti-Sequestosome 1 (SQSTM1) (AA 69-96), (N-Term) antibodySQSTM1 Reaktivität: Human, Maus, Ratte WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB: 1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Haltbarkeit
- 6 months
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- SQSTM1 (Sequestosome 1 (SQSTM1))
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Andere Bezeichnung
- Sqstm1
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Hintergrund
- Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures). Links ALIS to the autophagic machinery via direct interaction with MAP1 LC3 family members. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels. Adapter that mediates the interaction between TRAF6 and CYLD.
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Molekulargewicht
- 48163
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UniProt
- Q64337
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Pathways
- NF-kappaB Signalweg, Neurotrophin Signalübertragung, Autophagie
Target
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