Calnexin Antikörper (AA 560-592)

Produktnummer ABIN6242256

Der Kaninchen Polyklonal Anti-Calnexin-Antikörper wurde für WB, FACS und IHC (p) validiert. Er ist geeignet, Calnexin in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für Calnexin Antikörper (AA 560-592) (ABIN6242256)

Target: Calnexin (CANX)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Calnexin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB56768

Produktdetails anti-Calnexin Antikörper

Bindungsspezifität: AA 560-592

Homologie: M, Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CANX antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 560-592 amino acids from human CANX.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000. IHC-P: 1:25. FC: 1:25

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu Calnexin

Target: Calnexin (CANX)

Andere Bezeichnung: CANX

Hintergrund: Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor- mediated endocytosis at the synapse.

Molekulargewicht: 67568

UniProt: P27824

Pathways: MAPK Signalweg, Thyroid Hormone Synthesis