Rekombinanter Tyrosinase-Related Protein 1 Antikörper (CF®568)
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- Target Alle Tyrosinase-Related Protein 1 (TYRP1) Antikörper anzeigen
- Tyrosinase-Related Protein 1 (TYRP1)
- Antikörpertyp
- Recombinant Antibody
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser Tyrosinase-Related Protein 1 Antikörper ist konjugiert mit CF®568
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Applikation
- Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (IHC)
- Verwendungszweck
- Recombinant Rabbit Monoclonal anti-Tyrosinase Related Protein-1 (TYRP1/1564R), CF568 Conjugate
- Produktmerkmale
- This antibody reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogen
- Recombinant human full-length TYRP1 protein
- Klon
- TYRP1-1564R
- Isotyp
- IgG kappa
- Top Product
- Discover our top product TYRP1 Primärantikörper
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- Applikationshinweise
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Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris, 1 mM EDTA pH 9.0 for 10-20 min followed by cooling at RT for 20 min
- Immunohistology (formalin) 5-10 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunofluorescence 1-2 μg/mL
- Optimal dilution for a specific application should be determined by user
- Kommentare
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SK-MEL-23, SK-MEL-19, SK-MEL-30, SK-MEL-37 cells or Melanoma.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Protect from light
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- Target
- Tyrosinase-Related Protein 1 (TYRP1)
- Andere Bezeichnung
- Tyrosinase Related Protein-1 (TYRP1 Produkte)
- Synonyme
- CAS2 antikoerper, CATB antikoerper, GP75 antikoerper, OCA3 antikoerper, TRP antikoerper, TRP1 antikoerper, TYRP antikoerper, b-PROTEIN antikoerper, LOC397853 antikoerper, Trypsin antikoerper, hm:zeh0659 antikoerper, tyrp1 antikoerper, zgc:100893 antikoerper, B antikoerper, TYRP1 antikoerper, tyrp-1 antikoerper, TRP-1 antikoerper, Tyrp antikoerper, b antikoerper, brown antikoerper, isa antikoerper, tyrosinase related protein 1 antikoerper, protease, serine 1 L homeolog antikoerper, tyrosinase-related protein 1b antikoerper, tyrosinase-related protein 1 antikoerper, tyrosinase-related protein 1 L homeolog antikoerper, tyrosinase-related protein 1a antikoerper, TYRP1 antikoerper, prss1.L antikoerper, tyrp1b antikoerper, Tyrp1 antikoerper, tyrp1.L antikoerper, tyrp1 antikoerper, LOC100136490 antikoerper, tyrp-1 antikoerper, tyrp1a antikoerper
- Molekulargewicht
- 75 kDa
- Gen-ID
- 7306, 270279
- UniProt
- P17643
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